DeMAND

DOI: 10.18129/B9.bioc.DeMAND    

DeMAND

Bioconductor version: Release (3.8)

DEMAND predicts Drug MoA by interrogating a cell context specific regulatory network with a small number (N >= 6) of compound-induced gene expression signatures, to elucidate specific proteins whose interactions in the network is dysregulated by the compound.

Author: Jung Hoon Woo <jw2853 at columbia.edu>, Yishai Shimoni <ys2559 at columbia.edu>

Maintainer: Jung Hoon Woo <jw2853 at columbia.edu>, Mariano Alvarez <reef103 at gmail.com>

Citation (from within R, enter citation("DeMAND")):

Installation

To install this package, start R (version "3.5") and enter:

if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")
BiocManager::install("DeMAND", version = "3.8")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("DeMAND")

 

PDF R Script Using DeMAND
PDF   Reference Manual
Text   LICENSE

Details

biocViews GeneExpression, Network, NetworkEnrichment, Software, StatisticalMethod, SystemsBiology
Version 1.12.0
In Bioconductor since BioC 3.2 (R-3.2) (3 years)
License file LICENSE
Depends R (>= 2.14.0), KernSmooth, methods
Imports
LinkingTo
Suggests
SystemRequirements
Enhances
URL
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package DeMAND_1.12.0.tar.gz
Windows Binary DeMAND_1.12.0.zip
Mac OS X 10.11 (El Capitan) DeMAND_1.12.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/DeMAND
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/DeMAND
Package Short Url http://bioconductor.org/packages/DeMAND/
Package Downloads Report Download Stats

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